The Testmethod of the igevia-Metabolic Test

The igevia Metabolic Test is a DNA test - specifically a molecular genetic examination of your metabolic performance. This involves analysing genes that are relevant for determining the metabolic type and whose effect can be influenced by dietary or behavioural changes.

We restrict ourselves exclusively to analyses relating to your metabolism and do not investigate diseases or family relationships.

Test-Kit for home-use

The Metabolic Test contains the Test-Kit as well as detailed instructions for a simple oral swab - conveniently at your home in your familiar surroundings.

Simple oral swab

Using a swab, stroke along the inside of your cheek for 1 minute - done. Then send the swab in a special transport tube to our partner laboratory free of charge.

Analysis in the German Partner Laboratory

The laboratory method used is the polymerase chain reaction (PCR) – the most important method for studying the molecular fine structure of DNA, which carries the human genetic code. It was developed in 1983 by the biochemist Kary Mullis, who was awarded the Nobel Prize for Chemistry for this method.

Our partner laboratory in Germany analyses 23 different single nucleotide polymorphisms (SNP) in 19 genes in your sample. SNPs are genetic variants that have a positive, negative or neutral relationship to the core results of the igevia Metabolic Test.

Guide: Understanding SNP

Key results of the analysis

  • Metabolic Type/Sport Type
  • Tendency to be overweight
  • Feeling of Hunger
  • Yo-Yo effect

The evaluation is based on current scientific studies with a recognised research methodology and replicable results. Based on the results, you will receive personal recommendations that are in line with the German Society for Nutrition (DGE).

See Test-Results in detail

The 19 genes studied and their significance for metabolism & sport

Gene Meaning
ACTN3 A protein for fast and strong muscle contractions
ACVR1B A growth differentiation factor
ADRB2 A regulator of metabolic processes and influencer of training success
ADRB3 An influencing factor on energy metabolism
ALOX5AP A factor in fat conversion
APOA2 A factor in fat metabolism
APOA5 A regulator in fat metabolism
CKM A regulator of metabolic processes in muscle cells
FABP1 A fatty acid binding protein
FABP2 A fatty acid binding protein
FTO A regulator of body weight and fat burning
GHRL An appetizer
LEPR An appetite regulator
LPL A fat splitting enzyme
LTA A mediator of carbohydrate and fat metabolism
MC4R A factor in energy metabolism
MLXIPL A central regulator of metabolic enzymes
PPARD A transcription factor in fat metabolism
PYY A multiplier for secretion after ingestion

Testing your metabolism with igevia is so easy

Order & Delivery

You can obtain the igevia Metabolic Test in our Online-Shop or from one of our partners. Your online order will be delivered to your home free of shipping costs.

Implementation at home

The Metabolic Test contains the test kit and detailed instructions for a simple oral swab - in the comfort of your own home. You send your sample free of charge to our partner laboratory with the enclosed return box.

Laboratory analysis

Our partner laboratory uses the polymerase chain reaction (PCR) to analyse which of the six defined metabolic types you belong to. This procedure is the most important method for clarifying genetic questions.

Results-Report

The laboratory results are available in your igevia-Portal approx. two weeks after sending in the sample. The Results-Report provides information about your utilisation of carbohydrates, proteins and fatty acids, as well as your tendency to be overweight, Yo-Yo effect and hunger. On this basis, you will receive individual nutrition and sports recommendations.

Consultation

Use the Results-Report for a more detailed discussion with your nutritionist.

Order your Metabolic Test

Study Data

  • A.M. Coletta, B. Sanchez, A. O'Connor, R. Dalton, S. Springer, M. S. Koozehchian, P. S. Murano, C. R. Woodman, C. Rasmussen and R. B. Kreider: Alignment of diet prescription to genotype does not promote greater weight loss success in women with obesity participating in an exercise and weight loss program
  • Anke Hinney, Carla I. G. Vogel, Johannes Hebebrand: From monogenic to polygenic obesity: recent advances, Eur Child Adolesc Psychiatry (2010) 19:297–310, DOI 10.1007/s00787-010-0096-6
  • Carlos Rodríguez-Pardo, Antonio Segura, José J. Zamorano- León, Cristina Martínez-Santos, David Martínez, Luis Collado- Yurrita, Manel Giner, José M. García-García, José M. Rodríguez- Pardo, Antonio López Farré: Decision tree learning to predict overweight/obesity based on body mass index and gene Polymorphisms
  • Juan de Toro-Martín, Benoit J. Arsenault, Jean-Pierre Després and Marie-Claude Vohl: Precision Nutrition: A Review of Personalized Nutritional Approaches for the Prevention and Management of Metabolic Syndrome; Nutrients 2017, 9, 913; doi:10.3390/nu9080913
  • Laurence D Parnell*, Britt A Blokker, Hassan S Dashti, Paula-Dene Nesbeth, Brittany Elle Cooper, Yiyi Ma, Yu-Chi Lee, Ruixue Hou, Chao-Qiang Lai, Kris Richardson and José M Ordovás: CardioGxE, a catalog of gene-environment interactions for cardiometabolic traits; Parnell et al. BioData Mining 2014, 7:21
  • Pescatello L., Roth S. (eds.) Exercise genomics (Humana, 2011) (ISBN 978-1-60761-354-1; DOI 10.1007/978-1-60761-355-8)
  • Mori et al (J Physiol 587.23 (2009) pp 5577–5584) Genetic basis of inter-individual variability in the effects of exercise on the alleviation of lifestyle-related diseases
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